000			02829nam a22001457a 4500
008			221103b ||||| |||| 00| 0 eng d
100			_aMISLAW, OYINKEPREYE PETER _99597
245			_aEFFECT OF ANTIOXIDANT FEED SUPPLEMENTATION ON NEPHROLOGICAL AND HEPATIC BIOCHEMICAL INDICES IN BROILER BIRDS EXPOSED TO HEAT STRESS
250			_aDR. O.T KAYODE
260			_aIbafo _bBiological Science _c2022
300			_axi,; 75p.
520			_aFarmers all over the world suffer profit loss, as a result of unmanaged heat stress problems. This research project therefore, aims to investigate the effect of antioxidant feed supplementation on nephrological and hepatic biochemical indices in broiler birds exposed to heat stress and. 60 broiler chickens were completely randomized into four (4) groups of fifteen (15) birds each. They were exposed to varied temperatures of which group 1 to 4 were exposed to 25c, 30°c, 35°c and 40°c respectively. Each group was thereafter randomly re-classified into three (3) sub groups of five (5) birds each and assigned to A, B, and C based on treatment with un-supplemented feed (UF) supplemented feed with vitamin C/ascorbate (AF) and supplemented feed with cabbage juice (CF). The temperature exposure was for 12 hours daily from 7am to 7pm while the feed supplementation treatments was continuous for the twenty-eight (28) days exposure. Biochemical parameters such as: Nitric Oxide (NO), Total Cholesterol, High Density Lipoprotein (HDL), Triglyceride, Low Density Lipoprotein (LDL), Lipid Peroxidation, Total Protein, Superoxide Dismutase (SOD), and Catalase, were assayed for using standard procedure, and statistical analysis using SPSS. Results for the analysis showed significant increases (p < 0.5) in the concentration of Malondialdehyde (MDA), and Triglyceride. As well as significant reductions (p < 0.5) in the concentration of NO, HDL, Total Protein, and in the activity of SOD and Catalase for birds exposed to high temperatures (35℃ - 40℃), compared to the control birds (25℃). While there wasn’t any significant difference (p > 0.5) in Total Cholesterol, and LDL in the heat stressed birds compared to the control birds. Birds that were administered Vitamin C and cabbage juice, in addition to heat stress exposure however, had significantly reduced (p < 0.5) concentrations of MDA, Total Cholesterol, and Triglyceride, and significantly increased concentration of NO, HDL, Total Protein, and in the activity of SOD and Catalase in comparison to heat stressed birds (35℃ - 40℃) and control birds (25℃). In conclusion, cabbage juice shows a better ameliorative effect on heat stress in broilers compared to Vitamin C, therefore its therapeutic potentials can be explored in heat stress management.
650			_aBiochemistry _91335
942			_cTHS
999			_c6966 _d6966